Most applications are either sent via email or uploaded on a website, so it is unusual these days to print out a resume at all.
If you do print out your resume, either because a job ad requests it or because you are planning to drop it off at places where you wish to work, we recommend that you print it single-sided. This will make it easier for hiring managers to look at your resume by quickly flipping between pages.
It could also be helpful to paperclip the pages together, so it is easy for hiring managers to remove the scan each page individually if they want to keep a soft copy.